The CARD8 Inflammasome in HIV Pathogenesis & Disease Progression

Time: 12:00 pm
day: Day 1 - Track A - Morning


  • Learn how CARD8 is an inflammasome sensor for HIV protease activity
  • Discuss how HIV activates the CARD8 inflammasome to trigger pyroptosis of CD4+ T cells
  • Understand how inhibition of CARD8 activation prevents HIV-induced CD4 loss and disease progression