Identification of Structurally Distinct, Potent & Selective Brain Penetrant and Peripherally Restricted NLRP3 Inhibitors
Time: 2:30 pm
day: Day 2 - Track B - Afternoon
Details:
- Using our proprietary platform, we have identified numerous structurally distinct series of NLRP3 inhibitors that selectively bind to NLRP3 with high affinity
- The compounds comprise highly brain penetrant as well as peripherally restricted compounds
- Our lead compounds have a best-in-class potency and pharmacology profile and are highly active in vivo
