Identification of Structurally Distinct, Potent & Selective Brain Penetrant and Peripherally Restricted NLRP3 Inhibitors

Time: 2:30 pm
day: Day 2 - Track B - Afternoon

Details:

  • Using our proprietary platform, we have identified numerous structurally distinct series of NLRP3 inhibitors that selectively bind to NLRP3 with high affinity
  • The compounds comprise highly brain penetrant as well as peripherally restricted compounds
  • Our lead compounds have a best-in-class potency and pharmacology profile and are highly active in vivo

Speakers: