Inflammasome in Context: Crosstalk with PAMP Receptors via Purinergic Signals

Time: 11:30 am
day: Day 2 - Track A - Morning


  • The trigger threshold and tuning of Inflammasome activation depends on the state of pathogen associated molecular pattern (PAMP) receptors
  • Cross talk between the inflammasome and PAMP receptors is mediated via metabolic and purinergic signals in a cell type specific manner
  • The integrated cellular response arising from this cross talk can be highly non-linear and is related to specific cell death mechanisms