Novel ASC Antibodies Reduce Inflammasome Activation And Propagation Of Inflammation In Vitro & In Vivo

Time: 12:30 pm
day: Day 2 - Track A - Morning


  • Explore a panel of high affinity monoclonal antibodies
    was generated against different regions of ASC
  • Learn how these mAbs inhibit ASC polymerization and
    mitigate inflammation propagation in vitro
  • Discover how selected mAb improved functional
    outcomes in a mouse model of neuroinflammation