Targeting IL-1b Pathway for Cancer Immunotherapy

Time: 8:30 am
day: Day One


  • IL1b blockade was shown to inhibit chronic inflammation and prevent occurrence of lung cancer in a susceptible population
  • Single cell RNAseq analysis of primary tumor samples with in vitro treatment highlight cell targets and pathways for MoA
  • Mouse tumor models show a shift from immune suppression to activation with IL1b blockade