Translational Approaches for the Development of Novel NLRP3 Inhibitors

Time: 9:00 am
day: Day One

Details:

  • Explore ex vivo stimulated blood assays for early clinical evaluation of pharmacodynamics
  • Use of the D305N NLRP3 mechanistic mouse model for assessment of in vivo target cover
  • Discuss In vivo disease models for PK/PD assessment

Speakers: