Ashley Mansell

Company: Adiso Therapeutics

Job title: Head of Translational Sciences

Seminars:

Panel Discussion: Addressing the Current R&D Bottlenecks & Gaps in Inflammasome Therapeutic Research 9:30 am

What are the limitations of currently available animal models for recapitulating inflammasome-drug-tissue interactions? How/Should we be targeting inflammasomes locally at the sites of inflammation? How are we thinking about dosing for a known pharmacological effect/target engagement to specific organs without systemic exposure/immunosuppression? How are we thinking about dual/multi- inflammasome inhibition in terms of increasing drug…Read more

day: Day One

ADS032: A Novel Dual NLRP1 & NLRP3 Inhibitor to Target Inflammasome Inflammation 11:30 am

Learn about ADS032, a novel dual inflammasome inhibitor Discover how ADS032 reduces inflammation both in vitro and in vivo Evaluate how ADS032 reduces the inflammatory burden during inflammasome-related diseaseRead more

day: Day 2 - Track B - Morning