Humayun Sharif

Humayun Sharif

Company: Harvard Medical School

Job title: Instructor


Regulation of Inflammasomes Activity: A Structural Perspective of NLRP1 Inflammasome Regulation by DPP9 2:30 pm

Cryo-EM structure of NLRP1-DPP9 reveals a ternary complex that can sequester NLRP1-CT DPP9 quenches NLRP1-CT and serves as a checkpoint for activation of the NLRP1 inflammasome NLRP1 proteasomal degradation and disruption of ternary complex can activate NLRP1 inflammasomeRead more

day: Day 2 - Track A - Afternoon

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