Julia Hinterdobler

Company: Secarna Pharmaceuticals

Job title: Scientist

Seminars:

Leveraging the Power of ASOs to Target the Expression of NLRP3 for Enhanced Specificity of Inflammasome Inhibition 12:00 pm

Utilizing ASOs to specifically target NLRP3 expression for comprehensive inflammasome inhibition Demonstrating potent reduction in Caspase-1 activity and complete blockade of mature IL-1β release with NLRP3-specific ASOs Systemic administration of NLRP3-specific ASOs in a mouse model of CAPS shows prolonged survival and significant reduction in systemic inflammation, paving the way for potential ASO therapy in…Read more

day: Day 1