Conference Day One - Wednesday November 5, 2025

Download the Full Event Guide to explore detailed information about all sessions, speakers, and activities!

Full Event Guide

8:00 am Check-In & Breakfast Networking Session

8:55 am Chair’s Opening Remarks

Contextualizing Inflammasome-Related Disease Pathogenesis to Unveil Clinical Milestones

9:00 am Targeting NLRP3 in Myelodysplastic Syndrome: Initial Results from Phase Ib Trial of DFV890

  • Marc Pelletier Translational Immune Oncology, Associate Director, Novartis AG

9:30 am Preclinical & Clinical Evaluation of the Brain Penetrant NLRP3 Inhibitor, NT-0796 in Obesity & Cardiometabolic Disease

  • Alan Watt President & Chief Scientific Officer, NodThera Ltd.

10:00 am NULISA Assay Platform – Highest Sensitivity Single- to High-Plex Biomarker Analysis of Soluble Proteins & Fluid Biomarkers in Preclinical Models & for Clinical Development

  • Shidong Wang Senior Regional Business Manager, Alamar Biosciences Inc.

10:30 am Morning Refreshments & Speed Networking

Harnessing Mechanism-Based Biomarkers to Translate Inflammasome Activity into Clinical Efficacy

11:30 am NLRP3-Mediated Inflammation: Novel Strategy for Neurodegenerative & Cardiometabolic Disease Intervention

12:00 pm A New Predictive Frontier: Cellular-Level Inflammasome Biomarkers in Traumatic Brain Injury

  • Juan Pablo de Rivero Vaccari Associate Professor - Neurological Surgery, Neuroscience Graduate Program Faculty, Cellular Physiology & Molecular Biophysics G, University of Miami School of Medicine

12:30 pm Lunch & Networking

Cracking the Molecular Mechanisms to Reframe Inflammasome Research on Novel Targets

1:30 pm Cellular Stress and Inflammasome Activation in Chronic Inflammation & Tissue Repair

2:00 pm A Mechanistic Deep Dive: Tackling the Molecular Interplay with Caspases, Apoptosis & Pyroptosis

  • Olaf Groß Professor, Principal Investigator, University Medical Center Freiburg

2:30 pm Afternoon Refreshments & Poster Session

Building a Future-Proof Indication Strategy to Achieve Long-Term Clinical Success

3:30 pm Fireside Chat: What Each Stakeholder Needs – Repositioning Inflammasome Therapies for Clinical, Commercial & Capital Success

4:15 pm End of Conference Day One

4:30 pm Drinks Reception & Networking

5:30 pm Chair’s Closing Remarks

Full Event Guide
Pre-Conference Workshop Day
Day Two