Exploring Novel Modalities: Disabling the NLRP3 Inflammasome with a NEK7 Molecular Glue Degrader
Time: 10:30 am
day: Day 1
Details:
- Utilizing a NEK7 molecular glue degrader (MGD) as a potent and selective approach to targeting the NLRP3 inflammasome
- Path to the clinic with a NEK7 MGD
- NEK7 MGDs have tuneable tissue distribution profiles and can be highly brain penetrant
