Exploring Novel Modalities: Disabling the NLRP3 Inflammasome with a NEK7 Molecular Glue Degrader

Time: 10:30 am
day: Day 1


  • Utilizing a NEK7 molecular glue degrader (MGD) as a potent and selective approach to targeting the NLRP3 inflammasome
  • Path to the clinic with a NEK7 MGD
  • NEK7 MGDs have tuneable tissue distribution profiles and can be highly brain penetrant