Matthias Geyer

Company: Universitat Bonn

Job title: Director - Institute of Structural Biology

Seminars:

Leveraging Biochemical & Structural Analysis to Uncover Pyroptosis Inhibiting Nanobodies to Prevent Gasdermin D Pore Formation 1:30 pm

Exploring the effectiveness of six GSDMD-targeting nanobodies in inhibiting pore formation, elucidating their binding characteristics, stability, and impact on pyroptosis Revealing the atomic-level interactions between human GSDMD and two nanobodies for detailed insights into their mode of action and epitope recognition  Demonstrating the potential of nanobody-based intervention in preventing GSDMDmediated pore formation, presenting a promising…Read more

day: Day 1