Addressing the Challenge of Studying Non-Conserved Inflammasome Pathways in Preclinical Development
Time: 11:00 am
day: Day 2
Details:
- Explore the discrepancies between human and murine inflammasome pathways and their implications for recapitulating human-specific inflammatory responses
- Exploring the impact of replicating human heterogeneity in relative homogeneous mice to validate human systems
- Leveraging modeling techniques including humanized mouse models, advanced genetic engineering, and computational modeling to better mimic human immune responses and dissect pathway intricacies
